| Osteoporosis (OP) is a common bone metabolic disease. With the increase of aging in China, OP is a public health problem that is widely concerned in China today. Fructus ligustri lucidi (FLL), as a kidney-tonifying traditional Chinese medicine, is widely used in clinical practice and has unique advantages in the prevention and treatment of OP. Research has shown that FLL extract has a bone protective effect and reduces bone loss. However, its mechanism of action is not completely clear. Hence, this article employs databases like CNKI and PubMed to conduct a comprehensive search for pertinent domestic and international literature published within the last 15 years, utilizing keywords such as OP, FLL, osteogenesis, among others. Drawing upon existing research, this article primarily examines the preventive and therapeutic mechanism of FLL in relation to OP, including calcium balance, oxidative stress, bone metabolism, and parahormone effect. The aim is to furnish a foundation for future investigation on the role of FLL in preventing and treating OP, while also offering insights into the potential of traditional Chinese medicine in addressing this condition. |