| Objective To explore the correlation between the bone quantification of the thoracic vertebral and calcification of the coronary artery and thoracic aortic with routine CT. Methods General information, biochemical indexes, and coronary CTA of 217 patients were collected. Coronary and thoracic aorta calcification scores were measured and divided into calcified and non-calcified group. Cancellous and cortical bone mineral density, osteophyte score of T6-11 were measured. Comparisons, correlation analyses, and regression analyses between the groups were conducted. Results Calcified group of coronary and thoracic aorta had higher age, systolic blood pressure (SBP), blood glucose, and osteophyte scores. Calcified group had lower cancellous bone mineral density (P<0.05). Coronary calcification scores correlated positively with age, SBP, blood glucose, cortical bone mineral density, and osteophyte scores, and negatively with cancellous mineral bone density (P<0.05). Thoracic aorta calcification scores correlated positively with age, SBP, and osteophyte scores, and negatively with cancellous bone mineral density (P<0.05). Regression analysis showed that age, SBP, blood glucose, and osteophyte scores were independent risk factors for coronary artery calcification, and age, SBP, osteophyte scores were independent risk factors for thoracic aortic calcification (P<0.05). ROC curve showed that the combination of the independent risk factors improved the predictive value of coronary and thoracic aorta calcification risk. Conclusion Increased osteophyte score and decreased cancellous bone mineral density are significantly associated with coronary artery and thoracic aorta calcification. |