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| 由骨免疫学探讨中医药防治绝经后骨质疏松症研究进展 |
| Research progress of prevention and treatment of postmenopausal osteoporosis by traditional Chinese medicine based on bone immunology |
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| DOI：10.3969/j.issn.1006-7108.2024.08.021 |
| 中文关键词: 骨免疫 绝经后骨质疏松症 中医药 |
| 英文关键词:osteoimmunology postmenopausal osteoporosis traditional Chinese medicine |
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| 中文摘要: |
| 随着社会人口老龄化程度的日益严峻，骨质疏松症患者数量逐渐攀升，目前已成为严峻的公共健康问题。绝经后骨质疏松症（postmenopausal osteoporosis，PMOP）属于原发性骨质疏松症之一，由于女性绝经后雌激素缺乏，加快骨质流失，主要表现为疼痛、易发生骨折，给日常生活带来极大不便。骨免疫学着重于骨骼系统与免疫系统之间的联系，被激活的淋巴细胞释放各种细胞因子参与骨重塑的过程。中医药临床应用广泛，对PMOP治疗效果明显。本文基于骨免疫学，介绍中医药对骨代谢的影响，探讨中医药治疗PMOP的作用机制。 |
| 英文摘要: |
| With the aging of the social population increasingly serious，the number of patients with osteoporosis is gradually increasing， and it has become a serious public health problem. Postmenopausal osteoporosis(PMOP)is one of the primary osteoporosis.Due to the lack of estrogen in postmenopausal women， it accelerates bone loss， mainly manifested as pain and susceptibility to fractures，which brings great inconvenience to daily life.Bone immunology focuses on the link between the skeletal system and the immune system.Activated lymphocytes release various cytokines to participate in the process of bone remodeling. Traditional Chinese medicine is widely used in clinic and has obvious effect on PMOP treatment. Based on bone immunology，this paper introduced the effect of traditional Chinese medicine on bone metabolism and discussed the mechanism of traditional Chinese medicine in treating PMOP. |
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