| Osteoporosis (OP) is one of the important diseases with a global impact, which not only affects the quality of life of patients but also brings a huge burden to families and society. Current studies have shown that there is a correlation between anemia and bone mineral density and the incidence of osteoporosis, suggesting that anemia is an important controllable cause of osteoporosis. Anemia may interfere with bone metabolism through multiple pathways, leading to a decrease in bone mineral density and an increase in the risk of osteoporosis and fracture. On the contrary, some studies have suggested that anemia patients have higher bone mineral density, and even researchers believe that there is no direct correlation between them. Given this, the keywords of anemia, peripheral blood cells, bone mineral density, and osteoporosis were searched in Chinese literature databases such as CNKI and VIP. Anemia, peripheral blood cell count, bone mineral density, and osteoporosis were searched in English language literature databases such as Pubmed, Web of Science. The literature was screened, read, and summarized. On this basis, the research progress and possible mechanisms of the association between anemia and its related blood indicators with bone mineral density and osteoporosis are reviewed, to provide information for further research direction and clinical guidance. |