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| 由微循环运用中医药防治骨质疏松症的研究进展 |
| Research progress on the application of traditional Chinese medicine in the prevention and treatment of osteoporosis based on microcirculation |
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| DOI：10.3969/j.issn.1006-7108.2024.11.024 |
| 中文关键词: 中医中药 骨质疏松症 微循环 防治结合 |
| 英文关键词:traditional Chinese medicine osteoporosis microcirculation combination of prevention and control |
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| 中文摘要: |
| 随着人口老龄化的加重，骨质疏松症（osteoporosis，OP）的发病率逐年攀升，近些年中医药对于骨质疏松症这类慢性疾病的防治优势也渐渐突出。通过查阅相关文献发现，目前以微循环为切入点运用中医药防治OP的研究不断增加，但是缺少为临床和基础研究提供方向性的系统总结。该文通过系统总结，发现现阶段以微循环为切入点运用中医药防治OP主要包括：中医“虚、瘀、络脉”理论，补益肝肾、填精益髓、健脾补肾、活血化瘀为主的独活寄生汤、补肾通络汤、四物汤、桃红四物汤、六味地黄丸、左归丸等复方，补益脾肝肾类、活血化瘀类为主的丹参、黄芪、骨碎补、三七、人参等中药单体，以及针灸、中医传统功法易筋经等，可以改善微循环，提高骨密度，缓解骨质疏松症的进程，预防骨质疏松的并发症，改善OP人群的生存和生活质量。目前微循环的切入点仅停留在血管、血液、血流、脉管方面，后期对于淋巴系统、脂肪代谢、骨髓微环境、组织液的微循环为切入点可能成为中医药研究防治骨质疏松的新方向。 |
| 英文摘要: |
| With the aging of the population, the incidence of osteoporosis（OP）is also increasing year by year，and in recent years, the advantages of traditional Chinese medicine in the prevention and treatment of chronic diseases such as osteoporosis have gradually become prominent. Through the review of relevant literature，it is found that the current research on the use of traditional Chinese medicine in the prevention and treatment of OP with microcirculation as the starting point is increasing.But there is a lack of systematic summary for clinical and basic research. Through the research summary，it is found that at this stage，the use of traditional Chinese medicine to prevent and treat OP with microcirculation as the starting point mainly includes：the theory of“Deficiency，Stasis，and Nexus” in traditional Chinese medicine.It includes tonifying the liver and kidney，TianjingYisui，strengthening the spleen and kidney，invigorating blood and removing blood stasis,asDuhuoJisheng decoction，Bu-Shen-Tong-Luo decoction，Siwu decoction，TaohongSiwu Decoction，LiuweiDihuang pill，Zuogui wan and other compound formulas. It includes tonifying the spleen，liver and kidney，invigorating blood and removing blood stasis，and other traditional Chinese medicine monomers such as salvia，HuangQi,GuSuiBu，and SanQi，Ginsenoside notoginseng，as well as acupuncture，traditional Chinese medicine exercises Yijin Jing，etc. It can improve microcirculation，increase bone density，alleviate the process of osteoporosis，prevent complications of osteoporosis，and improve the survival and quality of life of OP population. However，at present，the entry point of microcirculation only stays in the blood vessels，blood，blood flow，and vasculature，and the microcirculation of the lymphatic system，fat metabolism，bone marrow microenvironment，and interstitial fluid may become a new direction for the prevention and treatment of osteoporosis in traditional Chinese medicine. |
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