“酒毒致痿”角度探讨酒精性骨质疏松症的发病机制
Pathogenesis of alcoholic osteoporosis from the perspective of "Alcohol Poisoning Causes Impotence"
  
DOI:10.3969/j.issn.1006-7108.2024.12.022
中文关键词:  酒毒致痿  酒精性骨质疏松  发病机制  骨代谢
英文关键词:alcohol toxicity causing impotence  alcoholic osteoporosis  pathogenesis  bone metabolism
基金项目:国家自然科学基金(8237153419);国家中医药管理局青年岐黄学者支持项目(国中医药人教发[2020]7号);黑龙江省重点研发计划(GZ20210136);黑龙江省中医药科研项目(ZHY2023-099);黑龙江省骨坏死基础与临床研究重点实验室
作者单位
王刚1 徐西林2* 晋世威1 贾青松1 1.黑龙江中医药大学黑龙江 哈尔滨 150040 2.黑龙江中医药大学附属第三医院 黑龙江 哈尔滨 150030 
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中文摘要:
      中医认为酒属湿热之品,过量饮用可致酒毒积聚,故长期大量饮酒具有易遏阳气,阻碍气机的致病特点;酒毒蕴结体内可影响脾胃、肝胆、肾等脏腑的功能,以致毒、虚、痰、瘀相互错杂、互为因果,进而影响骨代谢紊乱,加速骨量的丢失从而引起骨质疏松。酒精导致的骨质疏松常因无特异性表现常被患者忽视,绝大多数患者通常得不到及时的治疗来预防骨质疏松性骨折,从而使患者的生活质量下降并承担高昂的经济负担,甚至导致高死亡率。故而从“酒毒致痿”角度探讨骨质疏松的发病机制具有重要的意义,并从传统医学和现代医学不同角度阐明酒精性骨质疏松的研究进展,旨在引起饮酒人群的重视和为酒精性骨质疏松的防治提供思路。
英文摘要:
      Chinese medicine believes that wine is a hot and humid product, and excessive consumption can lead to the accumulation of alcohol poisoning, so long-term drinking of large quantities of alcohol is easy to curb yang qi, impede the pathogenic characteristics of qi; alcohol toxicity can affect the spleen, stomach, liver, gallbladder, kidneys and other internal organs of the function of the toxicity, deficiency, phlegm, blood stasis mixed with each other as a causal factor, which affects the disorders of bone metabolism, accelerate the loss of bone and thus cause osteoporosis. Alcohol-induced osteoporosis is often overlooked by patients because of its non-specific manifestations, and the majority of patients usually do not receive timely treatment to prevent osteoporotic fracture, which leads to a decline in the quality of life of the patients and a high economic burden, and even leads to a high mortality rate. Therefore, it is of great significance to discuss the pathogenesis of osteoporosis from the perspective of "alcohol toxicity causes impotence", and to clarify the research progress of alcoholic osteoporosis from different perspectives of traditional and modern medicine, aiming to draw the attention of people who consume alcohol and to provide ideas for the prevention and treatment of alcoholic osteoporosis.
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