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| 从“相火理论”辨治糖皮质激素性骨质疏松症 |
| Differentiation and treatment of glucocorticoid-induced osteoporosis from the theory of "phase fire" |
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| DOI：10.3969/j.issn.1006-7108.2024.12.026 |
| 中文关键词: 相火理论 糖皮质激素性骨质疏松 中医药 病机 治法 |
| 英文关键词:phase-fire theory glucocorticoid-induced osteoporosis traditional chinese medicine pathogenesis treatment |
| 基金项目:国家自然科学基金（82305279）；江西省中医药管理局科技计划(2023A0219) |
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| 中文摘要: |
| 以“相火理论”为指导，探析糖皮质激素性骨质疏松症（glucocorticoid-induced osteoporosis，GIOP）的病机及诊治，认为超量激素损害机体，引起相火妄动，致使机体阴阳失调，化髓成骨功能失常，产生GIOP。相火妄动为GIOP发生的根本病机。辨治当以平复相火为根本，以调整阴阳为纲要，治宜壮水之主，滋阴填精，以左归丸补之，或引火归元，温阳益气，以金匮肾气丸补之。基于“相火理论”辨治 GIOP 具有独特的应用价值，值得进行深入探讨，以期为临床防治GIOP提供新的思路。 |
| 英文摘要: |
| The pathogenesis, diagnosis, and treatment of glucocorticoid-induced osteoporosis were analyzed under the guidance of the "phase fire theory". It was concluded that excessive hormone levels damage the body, leading to wild movement of phase fire and resulting in an imbalance of Yin and Yang, dysfunction of marrow osteogenesis, and the development of GIOP. The fundamental pathogenesis of GIOP is related to the overreaction of fire. Treatment should be based on regulating the phase fire, adjusting Yin and Yang as a framework, strengthening water as the main focus, nourishing Yin and replenishing essence, supplementing Zuo-Gui Pills or returning phase fire to reduce excess fire energy, while warming Yang energy and supplementing Jin-Gui-Shen-Qi Pills. Differentiating and treating GIOP based on the theory of "phase fire" has unique practical value and deserves further discussion in order to provide new insights for clinical prevention and treatment of GIOP. |
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