中国骨质疏松杂志

中老年男性体格测量、体成分与定量CT腰椎骨密度相关性

The correlation between physical measurements, body composition analysis and lumbar bone density in middle-aged and elderly men based on quantitative CT

DOI：10.3969/j.issn.1006-7108.2025.02.008

中文关键词: QCT技术腰椎BMD 体格测量体成分分析相关性分析

英文关键词:QCT technique lumbar BMD physical measurement body composition analysis correlation analysis

基金项目:国家自然科学基金项目（82071884）；国家重点研发计划（2022YFC2010000；2022YFC2010001）；中原科技创新领军人才计划（244200510016）；河南省医学科技计划项目（SBGJ202302011）；河南省科技攻关计划项目（242102311121；242102311018；242102310299）

作者

单位

刘澳1 周菁2 孙永兵1 戚昕3 杜亚玮4 周阳1 李中林5 武肖玲6 邹智5 吕雪7 李永丽2 李昊8*

1. 郑州大学人民医院医学影像科，河南郑州 450003 2. 河南省人民医院健康管理学科河南省慢病健康管理重点实验室，河南郑州 450003 3. 新乡医学院，河南郑州 450003 4. 河南大学人民医院医学影像科，河南郑州 450003 5. 河南省人民医院医学影像科，河南郑州 450003 6. 河南省人民医院核医学科，河南郑州 450003 7. 河南省人民医院，河南郑州 450003 8. 阜外华中心血管病医院，河南郑州 451464

摘要点击次数: 143

全文下载次数: 0

中文摘要:

目的应用定量CT（quantitative computed tomography，QCT）技术测量腰椎骨密度（bone mineral density，BMD），探讨体格测量、体成分分析指标与中老年男性腰椎BMD的相关性。方法本研究为横断面研究，选取2018年1月至2023年2月在河南省人民医院健康管理中心接受体格检查的1 152名中老年男性体检者为研究对象，采集受试者年龄、身高、体重、血压、腰围、臀围、体脂肪质量与体肌肉质量数据，并计算体质量指数（body mass index, BMI）、体脂率（body fat percentage, BFP）与骨骼肌质量指数（skeletal muscle mass index, SMI）。同时使用QCT技术测量受试者腰椎BMD值，按照BMI进行分组，分为BMI正常组（18.5≤BMI＜24 kg/m2）、超重及肥胖组（BMI为＞24 kg/m2），并在两组中分别按照骨量诊断标准进行讨论。采用单因素方差分析，Pearson相关性分析和偏相关分析体格测量、体成分分析指标与腰椎BMD的相关性。结果在BMI正常组中，骨质疏松组的年龄、收缩压、腰臀比、BFP显著高于骨量正常组与骨量减少组，SMI显著低于骨量正常组与骨量减少组（P均<0.05）；超重及肥胖组中，骨质疏松组的年龄、收缩压、腰围、腰臀比与BFP显著高于骨量正常组与骨量减少组，SMI显著低于骨量正常组与骨量减少组（P均<0.05）。Pearson相关性分析结果显示，BMI正常组中腰椎BMD值与年龄、腰围、腰臀比、BFP呈显著负相关关系（r= – 0.385，r= – 0.122，r= – 0.199，r= – 0.168，P均<0.05），与SMI呈正相关（r=0.226，P<0.05）；超重及肥胖组中腰椎BMD值与年龄、收缩压、腰围、腰臀比、BFP呈显著负相关关系（r= – 0.379，r= – 0.087，r= – 0.101，r= – 0.187，r= – 0.199，P均<0.05），与SMI呈正相关（r=0.251，P<0.05）。在校正年龄因素后，偏相关分析分析结果显示，BMI正常组中腰椎BMD值与腰围、腰臀比、BFP呈显著负相关关系（r= – 0.157，r= – 0.212，r= – 0.134，P均<0.05），与SMI呈正相关（r=0.167，P<0.05）；超重及肥胖组中腰椎BMD值与腰围、腰臀比、BFP呈显著负相关关系（r= – 0.120，r= – 0.163，r= – 0.126，P均<0.05），与SMI呈正相关（r=0.159，P<0.05）。结论腰围、腰臀比、BFP、SMI与中老年男性体检人群腰椎BMD值密切相关，对肥胖和骨质疏松症的预防与管理具有一定临床价值。

英文摘要:

Objective To explore the correlation between physical measurement, body composition analysis indexes and lumbar spine bone mineral density (BMD) in middle-aged and elderly male based on Quantitative CT (QCT). Methods This study is a cross-sectional study, 1 152 middle-aged and elderly male physical examination subjects who underwent physical examination at the Health Management Center of Henan Provincial People’s Hospital from January 2018 to February 2023 were selected as the study subjects, and the data of age, height, weight, blood pressure, waist circumference, hip circumference, body fat mass and body muscle mass were collected, and body mass index (BMI), body fat percentage (BFP) and skeletal muscle mass index (SMI), and the BMD value of the lumbar spine was measured by QCT technology, and the subjects were divided into normal BMI group (18.5≤BMI<24 kg/m2) and overweight and obesity group (BMI >24 kg/m2), and the two groups were discussed according to the bone mass diagnostic criteria. One-way ANOVA, Pearson correlation analysis and partial correlation analysis were used to analyze the correlation between physical measures and body composition analysis and lumbar BMD. Results In the normal BMI group, the age, systolic blood pressure, waist-to-hip ratio and BFP of the osteoporosis group were significantly higher than those of the normal bone mass group and the osteopenia group, and the SMI was significantly lower than that of the normal bone mass group and the osteopenia group (all P<0.05). The results of Pearson correlation analysis showed that the BMD value of the lumbar spine was negatively correlated with age, waist circumference, waist-to-hip ratio and BFP in the normal BMI group (r= – 0.385, r= – 0.122, r= –0.199, r= – 0.168, all P<0.05), and positively correlated with SMI (r=0.226, P<0.05), the BMD value of lumbar spine was significantly negatively correlated with age, systolic blood pressure, waist circumference, waist-hip ratio and BFP in the overweight and obese groups (r= – 0.379, r= – 0.087, r= – 0.101, r= – 0.187, r= – 0.199, all P<0.05), and was positively correlated with SMI (r=0.251, P<0.05). After adjusting for age factors, the results of partial correlation analysis showed that the BMD value of lumbar spine was significantly negatively correlated with waist circumference, waist-hip ratio and BFP in the normal BMI group (r= – 0.157, r= – 0.212, r= – 0.134, all P<0.05) and positively correlated with SMI (r=0.167, P<0.05), and the BMD value of lumbar spine was significantly negatively correlated with waist circumference, waist-hip ratio and BFP in the overweight and obesity group (r= – 0.120, r= – 0.163, r= – 0.126, all P<0.05), and positively correlated with SMI (r=0.159, P<0.05). Conclusion Waist circumference, waist-to-hip ratio, BFP and SMI are closely related to the BMD value of lumbar spine in middle-aged and elderly men, which has certain clinical value for the prevention and management of obesity and osteoporosis.

查看全文查看/发表评论下载PDF阅读器

关闭