过伸复位手法联合PKP治疗双节段OVCF生物力学有限元分析
Biomechanical finite element analysis of extension reduction maneuver combined with percutaneous kyphoplasty (PKP) for two-segment osteoporotic vertebral compression fractures (OVCF)
  
DOI:10.3969/j.issn.1006-7108.2025.06.009
中文关键词:  过伸复位  椎体强化术  骨质疏松  椎体压缩骨折  有限元
英文关键词:extension reduction  vertebral augmentation surgery  osteoporosis  vertebral compression fracture  finite element
基金项目:国家自然科学基金(82260941)
作者单位
胡铁楠1 陈礼业1 秦大平1,2* 郑礼1 李磊1 张宏1 杨芳芳1 权祯1 宋敏1,2 张晓刚2 1.甘肃中医药大学甘肃 兰州 730000 2.甘肃中医药大学附属医院甘肃 兰州 730020 
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中文摘要:
      目的 应用生物力学有限元探讨过伸复位手法联合PKP治疗双节段骨质疏松性椎体压缩骨折术后伤椎运动节段模型与骨质疏松模型应力应变差异,为临床双节段OVCF患者术后残余症状的防治提供生物力学参考。方法 选取符合标准的L1、L2双节段OVCF患者1名以及骨质疏松患者1名作为研究对象,利用Mimics、Geomagic、SolidWorks、ANSYS软件建立三维有限元力学模型,在模型下表面椎体以固定支撑,上表面加以垂直向下的500 N的力以模拟人体受到正常的重力,再以模型上表面施加X、Y、Z正负方向7.5 N·m的扭矩,以模拟轴向、前屈、后伸、左侧弯、右侧弯、左旋转、右旋转七种工况,对比分析各个椎体皮质骨、松质骨、骨水泥等组织的应力分布状态。结果 成功建立了骨质疏松和过伸复位手法联合PKP治疗OVCF双节段术后生物力学模型,通过对比分析得出:经椎体强化术后双节段压缩骨折模型的整体力学效应与骨质疏松模型具有差异性,具体体现在等效应力大小与应力集中趋势方面。结论 结合既往文献研究说明了手法联合PKP治疗双节段OVCF虽改善了脊柱力学稳定性,但与正常未骨折骨质疏松患者模型仍有一定差距,可能与骨水泥团块在椎体内的分布和骨水泥材质相关,有待进一步研究。
英文摘要:
      Objective To investigate the biomechanical differences in stress and strain between the injured vertebral motion segment model and osteoporotic model after double-segment osteoporotic vertebral compression fracture (OVCF) treated with extension reduction combined with percutaneous kyphoplasty (PKP) using biomechanical finite element method, and to provide biomechanical reference for the prevention and treatment of residual symptoms after surgery in patients with double-segment OVCF. Methods One patient with double-segment OVCF at L1 and L2 and one patient with osteoporosis were selected as research subjects. Three-dimensional finite element mechanical models were established using Mimics, Geomagic, SolidWorks, and ANSYS software. The lower surface of the vertebral body was fixed and supported. A vertical downward force of 500 N was applied to the upper surface to simulate the normal gravity of the human body. Then, torques of 7.5 N·m in positive and negative directions of X, Y, and Z were applied to the upper surface of the model to simulate seven working conditions: axial, flexion, extension, left lateral bending, right lateral bending, left rotation, and right rotation. The stress distribution of cortical bone, cancellous bone, bone cement, and other tissues in each vertebral body was compared and analyzed. Results Biomechanical models of osteoporosis and postoperative OVCF treated with extension reduction combined with PKP were successfully established. Comparative analysis revealed that the overall mechanical behavior of the two-segment compressed fracture model after vertebral augmentation differed from that of the osteoporosis model, particularly in terms of equivalent stress magnitudes and stress concentration trends. Conclusion Combined with previous literature, this study demonstrates that extension reduction combined with PKP improves spinal biomechanical stability in two-segment OVCF patients, but differences remain compared to the osteoporosis model without fractures. These discrepancies may relate to the distribution of bone cement mass within the vertebral body and the material properties of the bone cement, warranting further investigation.
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