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| 由经脉理论探讨益气温经法对绝经后骨质疏松症的治疗 |
| Exploring the treatment of postmenopausal osteoporosis with the method of nourishing qi and warming meridians based on meridian theory |
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| DOI：10.3969/j.issn.1006-7108.2025.07.012 |
| 中文关键词: 绝经后骨质疏松症 经脉理论 益气温经法 中医中药 |
| 英文关键词:postmenopausal osteoporosis meridian theory nourish qi and warm meridians traditional Chinese medicine |
| 基金项目:国家自然科学基金面上项目(82074183) |
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| 中文摘要: |
| 经脉藏血气而养全身，与不同的脏腑有着密切联系，对骨骼的养护作用不容忽视。随着我国人口老龄化加剧，绝经后骨质疏松症患病率快速升高。绝经后骨质疏松症以肾虚血瘀为主要病机，因此虚瘀兼顾的益气温经法为其重要的治疗方法。该文通过总结经脉理论及中医对绝经后骨质疏松症的认识，详细阐释了经脉、脏腑、骨骼之间的复杂关系，并结合现代医学探讨益气温经法（以强骨饮为代表）对绝经后骨质疏松症的治疗机制。强骨饮通过调节p38 MAPK、AKT/mTOR等信号通路，抑制骨吸收并促进骨形成，临床研究表明其能显著提升骨密度、缓解疼痛症状。可为益气温经法治疗绝经后骨质疏松症提供理论依据和临床指导。 |
| 英文摘要: |
| The meridians store blood and qi to nourish the whole body and have a close connection with different viscera. Their role in the maintenance of bones should not be overlooked. With the intensification of population aging in China, the incidence of postmenopausal osteoporosis has increased rapidly. Postmenopausal osteoporosis is primarily characterized by kidney deficiency and blood stasis. Therefore, the method of benefiting qi and warming meridians, which takes both deficiency and stasis into account, is an important therapeutic approach. This paper summarizes the meridian theory and the understanding of postmenopausal osteoporosis in traditional Chinese medicine, elaborates on the complex interrelationships between meridians, viscera, and bones, and explores the treatment mechanism of the method of benefiting qi and warming meridians (represented by Qiangguyin) for postmenopausal osteoporosis in combination with modern medical science. Qiangguyin regulates signaling pathways such as p38 MAPK and AKT/mTOR to inhibit bone resorption and promote bone formation. Clinical studies have shown that it can significantly increase bone density and alleviate pain symptoms. This study offers a comprehensive theoretical framework and practical clinical guidance for treating postmenopausal osteoporosis using the method of benefiting qi and warming meridians. |
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