基于“卫气内伐”理论论治骨质疏松症
Treatment of Osteoporosis Based on the Theory of "Endo-Aggression of Defensive Qi"
投稿时间:2025-10-30  修订日期:2026-02-03
DOI:
中文关键词:  骨质疏松症  骨痿  昼夜节律  免疫  卫气内伐
英文关键词:Osteoporosis  Circadian Rhythm  Immunity  Internal Conflict of Defensive Qi
基金项目:江苏省中医药学会雏鹰腾飞项目(CYTF2024044);昆山市中医医院青年科学(2024QNJJ10)。
作者单位邮编
童铭豪 昆山市中医医院 215300
汪青 昆山市中医医院 
刘康 浙江中医药大学附属第二医院 
徐锋* 昆山市中医医院 215300
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中文摘要:
      骨质疏松症(Osteoporosis, OP)是一种严重影响中老年人生活质量的常见疾病。本文以《内经》“卫气内伐”理论为基础,构建了骨质疏松症从“卫气失位”到“卫气侵营”,最终发展为“卫气失律”的病机演进过程。该理论框架与慢性炎症、免疫代谢紊乱及昼夜节律异常等现代医学机制具有高度的契合性。在此基础上,本文进一步提出“固表—和营—调律”综合防治体系。该体系通过多层面、时序化的干预策略,能够有效整合抗炎、代谢调节及时间疗法等现代防治手段,为骨质疏松症的中西医结合防治提供了新思路与理论参考。
英文摘要:
      Osteoporosis (OP) is a common disease that severely affects the quality of life in middle-aged and elderly individuals. Based on the theory of “internal conflict of defensive qi” from the Inner Canon of Huangdi, this paper constructs a pathogenic progression of osteoporosis from “dislocation of defensive qi” to “defensive qi invading the nutrient aspect,” and ultimately to “loss of defensive qi regulation.” This theoretical framework demonstrates a high degree of consistency with modern medical mechanisms such as chronic inflammation, immune-metabolic disturbances, and circadian rhythm dysregulation. Building on this foundation, the paper further proposes a comprehensive prevention and treatment system termed “consolidating the exterior–harmonizing the nutrient aspect–regulating rhythm.” Through multi-level and time-sequential intervention strategies, this system can effectively integrate modern approaches such as anti-inflammatory therapy, metabolic regulation, and chronotherapy, offering novel perspectives and theoretical references for the integrated Chinese and Western medicine management of osteoporosis.
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