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| 从异病同治及共病角度探讨糖尿病性肌少-骨质疏松症 |
| Exploration of the treatment of diabetic osteosarcopenia from the perspective of treating different diseases with the same approach and comorbidity |
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| DOI：10.3969/j.issn.1006-7108.2025.11.013 |
| 中文关键词: 骨质疏松症 肌少症 中医疗法 糖尿病 并发症 |
| 英文关键词:osteoporosis sarcopenia traditional Chinese medicine therapy diabetes mellitus complications |
| 基金项目:浙江省自然科学基金项目（ZCLQ24H2701）;浙江省中医药传承创新人才支持计划（2023ZR104） |
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| 中文摘要: |
| 糖尿病作为全球性健康问题，其并发症多样且复杂，与多种慢性疾病密切相关。其中，肌少-骨质疏松症作为老年人常见的慢性肌肉骨骼疾病，在糖尿病患者中的合并患病风险显著高于普通人群。不仅严重影响患者的生活质量，还增加了临床治疗难度。糖尿病及肌少-骨质疏松症分属“消渴”“痿证”等病范畴。“痿证”的发生是可以由“消渴”逐渐发展而来的。糖尿病与肌少-骨质疏松症虽为“异病”，但具有共同的病因病机及延续性。本文从异病同治及共病角度，探讨糖尿病性肌少-骨质疏松症的中医发病机制、治法治则及以证统病进行实验研究的可行性，为中医药治疗老年慢性共病提供新思路。 |
| 英文摘要: |
| Diabetes, as a global health issue, presents diverse and complex complications closely associated with various chronic diseases. Osteosarcopenia (OS), a common chronic musculoskeletal disorder in the elderly, demonstrates significantly higher comorbidity risk among diabetic patients than the general population. This condition not only severely impacts patients' quality of life but also increases the difficulty of clinical management. In traditional Chinese medicine (TCM), diabetes and osteosarcopenia fall under the categories of wasting-thirst syndrome and wilting/atrophy syndrome, respectively. The development of wilting syndrome may progressively arise from wasting-thirst syndrome. Although diabetes and osteosarcopenia represent distinct pathological entities, they share common etiological mechanisms and pathological continuity. This paper explores the TCM pathogenesis, therapeutic principles, and feasibility of experimental research through syndrome-disease integration for diabetic osteosarcopenia from the perspectives of treating different diseases with same therapeutic methods and multimorbidity management. The findings aim to provide novel insights for TCM approaches in treating chronic comorbidities in elderly populations. |
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