| Objective To explore the association between appendicular skeletal muscle mass index
and serum vitamin D in postmenopausal women with T2DM. Methods 515 postmenopausalpatients with T2DM were included in this study. Collect general data, clinical indexes, body composition,bone mineral densityandskeletal muscle mass index,from all patients. According to serum vitamin D levels, all postmenopausal women with T2DM were grouped into four groups: group A with 25(OH)D of <10 ng/mL, group B with 25(OH)D of 10-20 ng/mL, group C with 25(OH)D of 20-30 ng/mL, and group D with 25(OH)D of≥30 ng/mL. At different vitamin D levels,the differences in skeletal muscle mass index, body composition and bone mineral densitywere analyzed. Results Serum vitamin D levels were positively correlated with ASMI,femoral neck bone density and total hip bone density (P< 0.05), negatively correlated with FMI, PBF, BMI (P< 0.05), and further multiple linear regression analysis showed that vitamin D levels were always positively correlated with ASMI after the inclusion of confounding factors (P<0.05). Conclusion Serum vitamin D levels in postmenopausal women with type 2 diabetes mellitus are positively correlated with limb skeletal muscle index, and serum vitamin D levels may affect skeletal muscle mass in postmenopausal women with type 2 diabetes mellitus. |