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| 身体圆度指数与骨质疏松发生风险的关系及其预测作用 |
| The relationship between body roundness index and the risk of osteoporosis and its predictive role |
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| DOI：10.3969/j.issn.1006-7108.2026.02.006 |
| 中文关键词: 身体圆度指数 骨质疏松 威布尔回归模型 |
| 英文关键词:body roundness index osteoporosis Weibull regression model |
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| 中文摘要: |
| 目的 探讨身体圆度指数（body roundness index，BRI）与50岁以上人群骨质疏松风险之间的非线性关系，并分析BRI在骨质疏松风险评估中的潜在应用价值。方法 采用纵向随访数据，数据来源于健康与退休研究（HRS）数据库。研究对象为4196名50岁以上人群。使用威布尔回归模型和分段威布尔模型，结合约登指数计算BRI的最佳截断点。对不同BRI水平的个体进行分析，评估BRI与骨质疏松风险之间的关系，并进一步验证BRI的独立预测作用。结果 当BRI＜7.77332时，每升高一个单位的BRI，骨质疏松发生风险增加6.6%（P＜0.01）；当BRI≥7.77332时，骨质疏松风险呈下降趋势，提示较高的BRI水平可能具有一定保护作用。结论 BRI水平与骨质疏松风险之间存在非线性关系。当BRI＜7.77332时，BRI升高与骨质疏松风险增加相关；当BRI≥7.77332时，BRI升高与骨质疏松风险降低相关。 |
| 英文摘要: |
| Objective To explore the nonlinear relationship between the body roundness index (BRI) and osteoporosis risk in individuals aged 50 and above, and to analyze the potential application value of BRI in osteoporosis risk assessment. Methods This study utilized longitudinal follow-up data from the Health and Retirement Study (HRS) database. A total of 4196 individuals aged 50 and above were included. The Weibull regression model and segmented Weibull model were used, along with the Youden index to calculate the optimal cutoff point for BRI. Individuals were analyzed at different BRI levels to assess the relationship between BRI and osteoporosis risk, and to further validate the independent predictive role of BRI. Results In the lower BRI range (i.e., BRI < 7.77332), for each unit increase in BRI, the risk of osteoporosis increased by 6.6% (P<0.01). when BRI ≥ 7.77332, the risk of osteoporosis showed a decreasing trend. Conclusion The analysis results indicated a nonlinear relationship between BRI and osteoporosis. when BRI < 7.77332, an increase in BRI is associated with a higher risk of osteoporosis; whereas when BRI≥7.77332, an increase in BRI is associated with a lower risk of osteoporosis. |
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