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| 骨质疏松症“未病”状态下运动干预策略 |
| Exercise intervention strategies for osteoporosis in the “Pre-disease” state |
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| DOI：10.3969/j.issn.1006-7108.2026.02.010 |
| 中文关键词: 骨质疏松症 未病 治未病 运动干预 中西医结合 |
| 英文关键词:osteoporosis prevention before illness (TCM concept) Pre-disease state of osteoporosis exercise intervention integration of traditional Chinese and Western medicine |
| 基金项目:国家自然科学基金交叉学部“未病”专项项目(T2341023)；2022年青年岐黄学者培养项目 |
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| 中文摘要: |
| 骨质疏松症（osteoporosis, OP）作为老龄化社会的高发性疾病，其早期防控已然成为全球公共卫生的优先议题。世界卫生组织全周期健康管理理念与中医“治未病”理论不谋而合，本团队提出以运动干预为核心的OP “未病”状态防控策略，关注OP发生、发展及转归的关键病理阶段，实现骨骼健康与生活质量的协同改善。未来需依托大规模多中心随机对照试验，构建“精准检测-个性干预-动态调控”多维健康管理体系，并融合智能传感技术与数据大模型工具，优化个体化干预路径，从而为“健康老龄化”目标提供循证支持。 |
| 英文摘要: |
| Osteoporosis (OP) is a high-incidence metabolic bone disease in the aging society, and its early prevention and control has become a priority issue of global public health. Based on the synergistic effect of the theory of “preventing disease before it occurs” in Chinese medicine and the concept of whole-cycle health management of the World Health Organization, our team has proposed the prevention and control strategy of “pre-disease” state of OP with exercise intervention as the core, which focuses on the key pathological stages of the occurrence, development, and prognosis of OP, and regulating the balance of bone metabolism, delaying bone mass loss and reducing the risk of fracture. Achieve synergistic improvement of bone health and quality of life. Evidence suggests that exercise interventions such as resistance training and weight-bearing aerobic exercise can significantly improve BMD. However, the lack of long-term compliance, unclear biomechanical mechanisms, and lack of interdisciplinary integration still limit clinical transformation. In the future, it is necessary to rely on large-scale multi-center randomized controlled trials to build a multi-dimensional health management system of “accurate detection - individualized intervention - dynamic regulation” and integrate intelligent sensing technology and data modeling tools to optimize the individualized intervention pathway, thus providing evidence-based support for the goal of “Healthy Aging”. |
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