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| 从营卫理论探讨绝经后骨质疏松症 |
| Explore postmenopausal osteoporosis from the perspective of Ying-Wei theory |
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| DOI：10.3969/j.issn.1006-7108.2026.02.015 |
| 中文关键词: 营卫交重 绝经后骨质疏松症 中医理论 |
| 英文关键词:Ying-Wei Jiao Chong postmenopausal osteoporosis traditional Chinese medicine theories |
| 基金项目:浙江省自然科学基金（LZ22H270002；ZCLQ24H2701）；浙江省中医药科技计划项目（2024ZR017） |
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| 中文摘要: |
| 绝经后骨质疏松症（postmenopausal osteoporosis, PMOP）是绝经后女性常见的骨骼疾病，严重影响患者生活质量并加重家庭经济负担。中医营卫理论与人体生理病理紧密相关，“营卫交重” 揭示了营气与卫气互根互用、动态平衡的关系。从营卫理论探讨，PMOP 的发生与营血亏虚致骨髓失养、卫气虚弱引发免疫炎症失衡、营卫失和破坏骨稳态有关。中药如黄芪桂枝五物汤、玉屏风散、桂枝汤等，通过调和营卫、补肾健脾、活血化瘀等作用，可改善 PMOP 患者骨代谢、缓解症状。基于“营卫交重”从营卫理论研究 PMOP 防治具有重要意义，有望为临床提供新思路与新方法。 |
| 英文摘要: |
| Postmenopausal osteoporosis (PMOP) is a common skeletal disorder in postmenopausal women, significantly impairing patients' quality of life and increasing family economic burdens. The Traditional Chinese Medicine (TCM) theory of Ying-Wei (nutrient-defense system) is closely related to human physiology and pathology. The concept of "dynamic balance and mutual reinforcement between Ying and Wei" (Ying-Wei Jiao-Zhong) reveals the interdependent relationship and harmonious equilibrium between Ying-Qi (nutrient Qi) and Wei-Qi (defensive Qi). From the perspective of Ying-Wei theory, the pathogenesis of PMOP may involve three aspects: deficiency of Ying-blood leading to marrow malnutrition, weakness of Wei-Qi causing immune-inflammatory imbalance, and Ying-Wei disharmony disrupting bone homeostasis. Chinese herbal formulas such as Huangqi Guizhi Wuwu Tang (Astragalus and Cinnamon Twig Five-Substance Decoction), Yupingfeng San (Jade Windscreen Powder), and Guizhi Tang (Cinnamon Twig Decoction) can improve bone metabolism and alleviate symptoms in PMOP patients through mechanisms including harmonizing Ying-Wei, tonifying kidney-spleen functions, and promoting blood circulation to remove stasis. Exploring PMOP prevention and treatment through the "Ying-Wei Jiao-Zhong" theory holds significant clinical value, offering potential novel strategies and approaches. This perspective may provide new insights for developing therapeutic interventions in clinical practice. |
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