小鼠骨质疏松模型建立方法与评价指标选择概述
A review on establishment and evaluation of mouse
  
DOI:
中文关键词:  小鼠  骨质疏松模型  骨性能指标
英文关键词:Mice  0P model  Bone indices
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作者单位
李昊 天津军事医学科学院卫生装备研究所 
张西正 天津军事医学科学院卫生装备研究所 
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中文摘要:
      骨质疏松症是中老年人中一种常见病、多发病,动物模型尤其是啮齿类动物模型是研究并治疗 骨质疏松的重要工具,并且由于近年来在骨生理学领域史无前例的有效应用,使得小鼠骨质疏松模型 越来越受到研究者们的关注。本文收集并整理了近年来小鼠骨质疏松模型建立方法及其相关评价指 标的选择,以期为今后有针对性的研究并治疗骨质疏松症提供全面的动物造模和关键指标选择的参考
英文摘要:
      osteoporosis ( 0P ) is a common senile disease. Anmial model, especially rodent model, has been considered as a signif.icant method to investigate and to treat OP. Due to the unprecedented application in bone physiology in recent years,mouse OP model has drawn more and more attenLion. This review collects and summarizes the estabiishment of mouse OP model and the evaluation and selection of the model,in order to provide references in future study on model estaWishment and key indices selection.
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