降钙素鼻喷剂治疗骨质疏松症骨痛的初步疗效观察
The first report of the treatment of bone pain associated with osteoporosis using the miacalcic nasal spray
  
DOI:
中文关键词:  降钙素  骨质疏松  骨痛
英文关键词:Calcitonion  Osteoporosis  Bone pain
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作者单位
张华俦 黄公怡 蔡恒江 100730 北京医院骨科 
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中文摘要:
      作者对20例经过胸腰椎X线撮片及双能骨密度测定证实为骨质疏松症的骨痛患者采用降钙索鼻喷剂治疗取得满意疗效。其中女性18例,男性2例,平均年龄63.4岁 治疗剂量为50IU鼻喷1次/天,持续 4周~3月不等,同时补充钙剂。本组病人显效 6例占30%,有效13例占65%,无效1例占5% ,总有效率为95% 。起效时间为用药后l~2周,以后日趋明显,短期应用降钙索不能提高脊柱及髋部的骨密度,但对骨质疏松症引起的骨痛具有良好的镇痛效果。
英文摘要:
      Bone pain associated with osteoporosis is very common disease in the orthopaedic field.During the past two years, 20 patients with bone pain which caused by osteoporosis had been treated with the miacalcic of nasal spray in our hospital. The BMD which measured by DEXA before the treatment in all patients were lower than that of the normal peop1e.In this study group,there are 18 female and 2 male. The age arranged from 45 to 8O years old,and the average age was 63.4 years.The treatment dose of miacalcic was 50IU per day and it lasted from 4 weeks to 3 months.Calcium supplement was also necessary during the treatment period.The good results had been achieved with 6 cases of excellent,13 patients gained good results and only 1 case failed. The relief of bone pain usually began at the first one or two weeks of the treatment, but no significant BMD increase had been found, even after3 months treatment.It could be concluded that the miacalcic of nasal spray is very effective for relieveing the bone pain.
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