骨质疏松性与肿瘤转移性椎体骨折患者代谢指标的比较
The comparison of metabolic indicators between patients with osteoporotic vertebral fractures and with tumor metastasizing vertebral fractures
  
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中文关键词:  骨质疏松性椎体骨折  肿瘤转移性椎体骨折  生化指标  脂代谢
英文关键词:Osteoporotic vertebral fractures  Tumor metastasizing vertebral fractures  Biochemical indicators  Lipid metabolism
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赵镇 金晖 何仕城 邓钢 210009南京东南大学附属中大医院内分泌科 
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中文摘要:
      目的 比较分析骨质疏松性与肿瘤转移性椎体骨折患者相关代谢指标及其关系。方法 回顾从2003年01月至2011年06月期间在我院介入血管外科行椎体成形术的146例骨质疏松性椎体骨折患者与111例肿瘤转移性椎体骨折患者的相关代谢指标,运用统计学方法进行统计。统计内容为:性别、年龄、椎体骨折数、手术次数、超敏C-反应蛋白、纤维蛋白原含量、血清总钙、磷、碱性磷酸酶(ALP)、空腹血糖、甘油三酯、总胆固醇、高密度脂蛋白、低密度脂蛋白。结果 两组患者在性别、年龄、手术次数、血清碱性磷酸酶、甘油三酯、总胆固醇、高密度脂蛋白水平间有统计学差异(P<0.05)。结论 骨质疏松性与肿瘤转移性椎体骨折患者在骨代谢及脂代谢方面存在差异,可帮助临床医生及时找出骨折病因,制定合理的治疗方案。
英文摘要:
      Objective To study the metabolic indicators between patients with osteoporotic vertebral fractures and with tumor metastasizing vertebral fractures and to analyze their relationship.Methods One hundred and forty-six cases of osteoporotic vertebral fractures and 111 cases of tumor metastasizing vertebral fractures,who had percutaneous vertebroplasty from January 2003 to June 2011,were retrospectively reviewed. The metabolic indicators,including gender,age,vertebral fracture number,frequency of surgical operations,high-sensitivity C-reactive protein,fibrinogen content,serum calcium,phosphorus,alkaline phosphatase(ALP),fasting blood glucose,triglyceride, total cholesterol,high-density lipoprotein,and low-density lipoprotein,were statistically analyzed.Results There were statistically differences in gender,age,frequency of surgical operations,serum alkaline phosphatase,triglyceride,total cholesterol,and high-density lipoprotein between the two groups(P<0.05).Conclusion There are differences of bone and lipid metabolic indicators between patients with osteoporotic vertebral fractures and with tumor metastasizing vertebral fractures.These indicators can help doctors to find the pathogenesis of the fractures and to set up a reasonable treatment strategy.
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