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| 脉冲电磁场对骨髓间充质干细胞作用研究进展 |
| Research progress of mechanism of pulsed electromagnetic field on bone marrow mesenchymal stemcells |
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| DOI：10.3969/j.issn.1006.7108.2012.08.025 |
| 中文关键词: 脉冲电磁场 骨髓间充质干细胞 分化 增殖 |
| 英文关键词:Pulsed electromagnetic field ( PEMFs ) Bone marrow mesenchymal stem cells ( BMMSCs ) Differentiation Proliferation |
| 基金项目:广东省科技计划项目（2011B031800147） |
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| 中文摘要: |
| 目的 旨在探究脉冲电磁场对骨髓间充质干细胞作用条件及机制，以促进其临床应用。方法 由第一作者应用计算机检索PubMed、中国期刊全文数据库（CNKI)、维普数据库和万方数据库1997- 05/2012-03 相关文献。在标题、摘要、关键词中以“ pulsed electromagnetic field( PEMFs ),bone marrow mesenchymal stem cells( BMMSCs )，differentiation，proliferation” 或“脉冲电磁场，骨髓间充质干细胞，分化，增殖”为检索词进行检索。选择文章内容与脉冲电磁场有关者，同一领域文献则选择近期发表在权威杂志文章。初检得到184篇文献，根据纳入标准选择41篇文献进行综述。结果与结论 在一定条件下，脉冲电磁场对骨髓间充质干细胞的增殖及分化有促进作用，对于骨质疏松、骨不连等临床应用有一定意义。 |
| 英文摘要: |
| Objective To explore the mechanism of pulsed electromagnetic field on bone marrow mesenchymal stem cells in order to promote its clinical application. Methods A computer-based online search of PubMed database，CNKI database，VIP database，and Wanfang database from May 1997 to May 2012 was performed to search related articles with the key words of pulsed electromagnetic fields ( PEMFs ), bone marrom mesenchymal stem cells ( BMMSCs )，differentiation,and proliferation in English or Chinese. Literatures related to pulsed electromagnetic field were selected. Articles published lately in authorized journals were preferred in the same field. A total of 184 literatures were primarily selected,and 41 documents were involved for summary according to inclusion criteria. Results and Conclusion Under certain conditions,pulsed electromagnetic fields promote proliferation and differentiation of bone marrow mesenchymal stem cell. This can be used for osteoporosis，bone non-union，and other clinical applications. |
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