绝经妇女腰椎及髋关节定量cT骨密度测量诊断骨质疏松的初步研究
The comparison of spine and hip QCT BMD measurements in diagnosis of osteoporosis in thepostmenopausal women
  
DOI:
中文关键词:  骨质疏松  骨密度测量  定量  计算机体层摄影
英文关键词:0steoporosis  Bone mineral densiLy measuremenL  Quantitative  Computed tomography
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作者单位
邓德茂 广西中医药大学第一附属医院放射科 
何欣 广西中医药大学第一附属医院放射科 
李家言 广西中医药大学第一附属医院放射科 
张建 广西中医药大学第一附属医院放射科 
黄增超 广西中医药大学第一附属医院放射科 
袁文昭 广西中医药大学第一附属医院放射科 
孙伟杰 北京积水潭医院放射科 
王玲 北京积水潭医院放射科 
程晓光 北京积水潭医院放射科 
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中文摘要:
      目的比较绝经后妇女L2-L4椎体及髋关节两个部位的定量CT骨密度(BMD )测量诊断骨 质疏松的效能。方法175例绝经妇女,年龄48-96岁,平均年龄为69 ±9岁。同时QCT测量L2-L4椎体的平均体积骨密度及髋关节类DXA的面积骨密度,右股骨颈和全髋二个感兴趣区(ROI )。 采用国际临床骨密度学会(ISCD )QCT骨质疏松诊断标准(<80 mg/cm3 )和WHO髋关节DXA骨密 度诊断标准即股骨颈或全髋感兴趣区的T值(-2.5 SD )进行骨质疏松诊断。比较二者诊断骨质疏 松的效能。结果175绝经后妇女中,QCT骨密度测量腰椎部位骨密度值骨质疏松的检出率是44%( 77/175 )。如果采用髋部检查股骨颈部位为11%.( 19/175 ),全髋部位为14%.( 24/175 ),或二者任一 部位为18%_( 31/175 )。如果只做腰椎,不做髋关节,有7人漏诊,而如果只做髋关节,不做腰椎会漏 诊44人。结论采用QCT骨密度测量,绝经妇女腰椎检查骨质疏松检出率为44%_,而髋部检查检出 率为18%_。采用QCT骨密度测量,测量腰椎一个部位就可以诊断骨质疏松。
英文摘要:
      To compare the efficacy of spinal and hip QCT BMD measurement in the diagnosis of osteoporosis of postmenopausai women. Methods 175 menopausal women aged 48 to 96 years old ( 69 土 9 years ) were recruited in this study. The average volumeLric bone densiLy of L2 - 4 and DXA like area bone mineral density of the hip were measured by QCT. According Lo Lhe international society for clinical densitometry ( ISCD ) QCT diagnosis criLeria of osLeoporosis ( <80 mg/cm3 ) and WHO hip DXA BMD criteria, i.e. , the score of f^ioral neck or to tal hip ROI was below 2.5 SD, then the detecting rate of osLeoporosis in the spine and hip was calculaLed and Lheir perfomiance in diagnosis of osLeoporosis was analyzed by statics. Results The detecting rate of osteoporosis was 44%' ( 77/175 ) in the lumbar spine by QCT in 175 postmenopausal women,and the number was 11%' ( 19/175 ) for femoral neck,14%' ( 24/175 ) for to tal hip ROI,and 18%' ( 31/175 ) for either of them,respectively. 7 cases would be missed only by the lumbar spine, but 44 cases would be missed only by the hip. Conclusions The deLecL raLe of osteoporosis was 44%' in the lumbar spine by QCT,and Lhe rate was 18%' by hip examination in the postmenopausal women. Measurement of BMD in the spine by QCT will be sufficienL to diagnose osteoporosis.
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