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| 降钙素基因多肽对骨代谢的影响 |
| Effect of calcitonin gene-related peptide on bone metabolism |
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| DOI：10. 3969/j. issn. 1006-7108. 2012. 12. 021 |
| 中文关键词: 骨质疏松 降钙素 骨代谢 |
| 英文关键词:Osteoporosis Calcitonin Bone metabolism |
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| 中文摘要: |
| 根据骨质疏松的发病机制不同，可分为原发性骨质疏松和继发性骨质疏松，原发性骨质疏松又可分为绝经性骨质疏松和老年性骨质疏松。骨质疏松是由多种发病因素共同作用的结果，在各型骨质疏松中，降钙素均发挥重要的调节作用。近年研究发现某些神经、血管活性肽，如降钙素基因多肽(Calcitonin gene-related peptide，CGRP），在结构和功能上与降钙素具有一定的相似性。本文将降钙素基因多肽对骨代谢影响的相关研究进展作以下综述。 |
| 英文摘要: |
| According to different pathogenesis，osteoporosis is classified as primary osteoporosis and secondary osteoporosis. Primary osteoporosis can be classified as postmenopausal osteoporosis and senile osteoporosis. Osteoporosis is a co-working result of multiple pathogenic factors. Calcitonin plays an important regulatory role in all types of osteoporosis. In recent years, researches show that some nerve and vascular
active peptides， such as calcitonin gene-related peptide ( CGRP )，have similarity with calcitonin in structure and function to some extent. This paper reviews the related research progress in the effect of CGRP on bone metabolism. |
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