绝经后妇女骨量减低筛查及早期干预研究
Screening of bone mass lose in postmenopausal women and early intervention study
  
DOI:10. 3969/j. issn. 1006-7108. 2012. 12. 023
中文关键词:  绝经后妇女  骨量减低  干预研究
英文关键词:Postmenopausal women  Bone mass loss  Intervention study
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作者单位
白颖 田营营 钟兰兰 胡晓 刘杰 100091北京解放军第309医院骨科四区 
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中文摘要:
      目的 观察在骨量减低阶段进行干预对骨质疏松的发生及骨折的预防作用,探寻最佳的骨质疏松健康管理原则,从而为更早期防治骨质疏松提供理论依据。方法 到本医院行双光能X线骨密 度仪(DEXA NORLAND)测定的骨量减低绝经后的妇女273例,分为干预组与对照组,研究时间为1 年。所有数据均用SPSS统计软件进行分析,结果用x±s表示,组间比较采用t检验,P<0. 05显示差异具有统计学意义。结果 骨量减低阶段进行干预对骨质疏松的发生及骨折的预防作用显著,探寻出最佳的骨质疏松健康管理原则。结论 在骨量减低期间即进行生活方式及药物干预,观察不同干预方式对骨密度、骨代谢指标的影响程度,通过不同方式干预,骨量减低的绝经后妇女转归情况及对骨质疏松性骨折的预防,为更早期防治骨质疏松提供理论依据。
英文摘要:
      Objective To observe the effect of intervention during the period of bone mass loss on the occurrence of osteoporosis and the prevention of fractures, and to explore the best management principle of osteoporosis, thus providing theoretical basis for earlier prevention and treatment of osteoporosis. Methods A total of 273 postmenopausal women who were diagnosed as bone mass loss using dual energy X-ray absorptiometry ( DEXA,NORLAND ) in our hospital were selected. They were divided into intervention group and control group. The study lasted for 1 year. All the data were analyzed using SPSS statistical software, and the results were expressed as :x土 s. T test was used for comparison between the groups. P <0.05 was considered statistically significant. Results Intervention during the periods of bone mass loss had obvious effect on the occurrence of osteoporosis and the prevention of fractures. The best health management principles of osteoporosis were explored. Conclusion Lifestyle and drug intervention should be performed during the period of bone mass loss. The effects of different intervention on bone mineral density and bone metabolism are observed. Through different intervention ways to reduce bone loss in postmenopausal women and to prevent osteoporotic fractures,we provide theoretical basis for early prevention and treatment of osteoporosis.
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