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| 绝经后女性腹部脂肪、椎旁肌肉和骨密度的相关性 分析 |
| Abdominal fat, paraspinal muscle size and bone mineral density in postmenopausal woman |
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| DOI：10.3969/j.issn.1006-7108.2017.05.011 |
| 中文关键词: 腹部脂肪 椎旁肌肉；骨密度 |
| 英文关键词:Abdominal fat Paraspinal muscle Bone mineral density |
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| 中文摘要: |
| 目的 评价绝经后女性腹部脂肪和椎旁肌肉与骨密度的相关性。方法 选取2016年4月至2016年10月就诊于我院 的绝经后女性75例，年龄45?83(62. 2 ± 9. 1)岁，应用DXA( dual-energy X-ray absorptiometry ,DXA)测量腰椎骨密度，再对受检者行腹部CT扫描,并在后处理工作站选定平脐水平的CT片，勾画出腹部脂肪和椎旁肌肉的面积。为了进一步分析，将样本 根据体重指数分为2组，A组18.5≤BMI<24，B组BMI≥24。结果 腰椎骨密度与体重指数、腹部皮下脂肪、腹部内脏脂肪、 腹部总脂肪、腰大肌及竖脊肌均呈正相关（r = 0. 264,P=0. 022；r = 0. 244,P=0. 035；r = 0. 286,P = 0. 013；r = 0. 298,P =0.009； r=0. 371 ,P=0. 001 ；r = 0. 258 ,P=0. 025)。通过将BMI( body mass index)分为2组后得到结果：A组骨密度主要与腰大肌和 竖脊肌呈正相关（r=0. 479,P=0.011；r = 0. 424,P=
0. 028)，B组骨密度主要与内脏脂肪和总脂肪呈正相关（r = 0. 318 , P = 0.028;r=0.339,P =0.019)。结论 目前研究结果表明，对于绝经后女性而言，腹部脂肪和椎旁肌肉对骨密度具有保护作用， 适当的体育锻炼和保持正常的体重更有利于预防骨质疏松症。 |
| 英文摘要: |
| Objective To evaluate the correlation of bone mineral density (BMD) with abdominal fat and paraspinal muscle size in postmenopausal woman. Methods This study was conducted during the period of April 2016 to October 2016 in 75 postmenopausal women aged 45 to 83 (62. 2 ± 9. 1 ) years. BMD of the lumbar spine was measured by dual-energy X-ray absorptiometry (DXA) and the outline of abdominal fat and paraspinal muscle size on the umbilical level of CT was drawn by using the post-processing workstation. In a further analysis, the study population was stratified into two groups according to BMI (body mass index). Group A 18. 5≤ BMI <24; Group B BMI≥ 28. Results BMD of the lumber spine was correlated with BMI, abdominal subcutaneous fat, abdominal visceral fat, total abdominal fat, psoas muscle and spinal erector muscle (r = 0. 264，P = 0. 022； 0.244，P =0. 035 ； r = 0.286，P =0.013； r = 0.298，P = 0.009; r = 0. 371, P = 0.001; r = 0. 258, P = 0.025， respectively). After BMI stratification, in Group A, BMD had significant correlation with psoas muscle and erecter spinae muscle (r=0. 479，P=0.011; r = 0. 424, P=0. 028). In Group B，BMD had significant correlation with abdominal visceral fat and total abdominal fat (r = 0. 318, P =0. 028 ； r = 0. 339, P =0. 019) . Conclusion The results of the current study demonstrated that the abdominal fat and paraspinal muscle had a protective effect on BMD in postmenopausal women. Our results suggest that suitable physical exercise and maintaining normal body weight may play a role in the prevention of osteoporosis. |
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