多发性骨髓瘤脊柱病变临床及MRI分析
MRI and clinical features of multiple myeloma in spine
  
DOI:
中文关键词:  多发性骨髓瘤  磁共振成像  脊柱  骨质疏松症
英文关键词:Multiple myeloma  Magnetic resonance imaging  Spine  0steoporosis
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作者单位
于爱红 北京积水潭医院放射科 
程克斌 北京积水潭医院放射科 
梁伟 北京积水潭医院放射科 
程晓光 北京积水潭医院放射科 
张晶 北京积水潭医院放射科 
顾翔 北京积水潭医院放射科 
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中文摘要:
      目的探讨多发性骨髓瘤脊柱病变临床及MRI影像学特点。方法回顾性分析31例脊柱多发 性骨髓瘤患者的临床及MRI资料,全部病例经穿刺病理及细胞学检查确诊为多发性骨髓瘤。其中男 16例,女性15例,发病年龄45耀77岁,平均年龄51.6岁。结合临床资料,分析其MRI表现特点。结 果本组正常型1例;局灶型9例,表现为多个脊椎或单个脊椎内大小、数目不等的病灶;弥漫型14 例,表现为扫描范围内所有脊椎多发性弥漫异常信号;“椒盐型”8例,弥漫脊椎受累,T1WI、T2WI均 表现为弥漫性斑点状高、等、低混杂信号。28例累及椎体及附件;15例形成椎旁软组织肿块。8例增 强后患者,病灶均表现为不同程度的强化。结论脊柱多发性骨髓瘤MR工具有一定的特点,对 于临床以颈、胸、腰背痛就诊的中老年患者,应临床与MRI表现结合,进行综合诊断和鉴别诊断。
英文摘要:
      Objective To study The MRI and clinic features of The vertebral mulLiple myeloma (MM ). Methods The MRI and clinic feaLures of 31 paLienLs with verLebral MM proved by histology were retrospecLively analyzed. The mean age of Lhe paLienLs( 16 men and 15 women, range 45- 77 years ))as 51. 6 years old. Results The vertebral MM was classified inLo Lhe foUowing four Lypes : nomial Lype in 1 case, focal MM in 9 cases in which Lhe lesions scaLLered in one verLebra or muiLiple vertebrae with different size and number,diiluse MM in 14 cases in which all the verLebrae were involved, and “ Salt with pepper ” patterns in 8 cases which were characterized by diiluse spoL-like hyper-, iso-and hypo-inLensiLy. Both vertebral body and posterior elements were involved in 28 cases. Paravertebral soft Lissue mass was seen in 15 cases, and differenL enhancemenL was shown in 8 cases. Conclusion The verLebral MM has some feaLures on MRI. In elderly paLienLs wiLh pain of the spine, it is necessary to combine MRI feaLures with clinical presenLaLion in diagnosis and differenLial diagnosis of MM.
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